The Office of Scientific and Technical Information (OSTI) is a component of the Office of Science within the U.S. Department of Energy (DOE). The Energy Policy Act PL 109–58, Section 982, called out the responsibility of OSTI: "The Secretary, through the Office of Scientific and Technical Information, shall maintain with the Department publicly available collections of scientific and technical information resulting from research, development, demonstration, and commercial applications activities supported by the Department."

OSTI provides access to energy, science, and technology information through publicly available web-based systems, with supporting tools and technologies to enable information search, retrieval and re-use.

OSTI's entire line of electronic products may be accessed through its home page, where users may search multiple databases with one query.