Beauregard married Marie Laure Villeré in 1841. She was from a prominent Louisiana Creole family. The marriage brought him social connections and solidified his position within the Creole community.

Marie Laure Villeré died in 1850, leaving Beauregard a widower with several children. Her death was a significant personal loss for him.

Beauregard married Caroline Deslonde in 1860. She was also from a prominent Louisiana family. This marriage further strengthened his social standing.

Caroline Deslonde died in 1864 during the Civil War, adding to the personal hardships Beauregard faced during that time. Her death impacted him deeply amidst the turmoil of the war.

Beauregard was a father to several children from his two marriages. He strived to provide for his family and maintain strong relationships with them despite his military obligations and personal tragedies.