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P2RY1
P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.
The product of this gene, P2Y1 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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P2RY1
P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.
The product of this gene, P2Y1 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.