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1-alkyl-2-acetylglycerophosphocholine esterase
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1-alkyl-2-acetylglycerophosphocholine esterase
The enzyme 1-alkyl-2-acetylglycerophosphocholine esterase (EC 3.1.1.47) catalyzes the reaction
The former is also known as platelet-activating factor. There are multiple enzymes with this function:
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase. Other names in common use include 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase, and alkylacetyl-GPC:acetylhydrolase. This enzyme participates in ether lipid metabolism.
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes PDB: 1BWP, PDB: 1BWQ, PDB: 1BWR, PDB: 1ES9, PDB: 1FXW, PDB: 1VYH, and PDB: 1WAB.
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1-alkyl-2-acetylglycerophosphocholine esterase
The enzyme 1-alkyl-2-acetylglycerophosphocholine esterase (EC 3.1.1.47) catalyzes the reaction
The former is also known as platelet-activating factor. There are multiple enzymes with this function:
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase. Other names in common use include 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase, and alkylacetyl-GPC:acetylhydrolase. This enzyme participates in ether lipid metabolism.
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes PDB: 1BWP, PDB: 1BWQ, PDB: 1BWR, PDB: 1ES9, PDB: 1FXW, PDB: 1VYH, and PDB: 1WAB.