Prison Nurse is a 1938 American drama film directed by James Cruze and written by Earl Felton and Sidney Salkow. It is based on the 1934 novel Prison Nurse by Louis Berg. The film stars Henry Wilcoxon, Marian Marsh, Bernadene Hayes, Ben Welden, Ray Mayer and John Arledge. The film was released on March 1, 1938, by Republic Pictures.

A typhoid fever breaks out in a state prison and the prison's only doctor gets sick, there are only 3 nurses at the prison to administer vaccines and take care of the inmates, but some are planning to use the chaos to escape.