Chamdo, officially Qamdo (Tibetan: ཆབ་མདོ, Wylie: chab mdo, ZWPY: qamdo) and also known in Chinese as Changdu (Chinese: 昌都; pinyin: Chang Du), is a prefecture-level city in the eastern part of the Tibet Autonomous Region, China. Its seat is the town of Chengguan in Karuo District. Chamdo is Tibet's third largest city after Lhasa and Shigatse.

Chamdo is divided into 11 county-level divisions: one district and ten counties. The main district is Karuo District. Other counties include Jonda County, Gonjo County, Riwoche County, Dengqen County, Zhag'yab County, Baxoi County, Zognang County, Maarkam County, Lhorong County, and Banbar County.

Wang Qimei and Zhang Guohua led 40,000 People's Liberation Army soldiers in an attack against the 8,000 soldiers of the Tibetan Army defending Chamdo on 7 October 1950. Over 5,700 Tibetans died after fighting 21 battles by 19 October, and Provincial Governor Ngapoi Ngawang Jigme was captured. The fall of Chamdo resulted in the Tibetan government submitting to China's demands.

On 11 July 2014 Chamdo Prefecture was upgraded into a prefecture-level city.

Languages spoken in Chamdo include Khams Tibetan and the Chamdo languages of Lamo, Larong, and Drag-yab.

From 1951 to 1954, the Chinese army constructed a 2,300 kilometre long highway from Ya'an to Lhasa that went through Chamdo.

The city is subdivided into 11 county-level divisions: 1 district and 10 counties.

Chamdo has a humid continental climate (Köppen: Dwb) in the Karub District and an alpine subarctic climate (Köppen: Dwc) in other counties.