SWAT Kats: The Radical Squadron is an American animated television series created by Christian and Yvon Tremblay and produced by Hanna-Barbera. The series takes place in the fictional metropolis of Megakat City populated by anthropomorphic felines, known as "kats", and follows two vigilante pilots who possess a futuristic fighter jet with an array of weaponry. Throughout the series, they face various villains, as well as competition from Megakat City's militarized police force, called the Enforcers.

The series originally premiered and aired on the syndication block The Funtastic World of Hanna-Barbera, as well as on TBS Superstation (as a part of the Sunday Morning in Front of the TV block) from 1993 to 1995. Every episode of the series was directed by Robert Alvarez. The bulk of the series was written by Glenn Leopold (15 episodes) or Lance Falk (9 episodes). Jim Stenstrum contributed two episodes, while David Ehrman, Von Williams, Eric Clark (with Lance Falk), Mark Saraceni, and Jim Katz all contributed one episode each. Nine episodes from Season 1 are animated by Hanho Heung-Up Co., Ltd., four episodes from Season 1 and all episodes from Season 2 are animated by Mook Animation Inc.

A revival series, titled SWAT Kats: Revolution, is under development, with both the Tremblay brothers and the Toonz Media Group at the helm.

Jake "Razor" Clawson (voiced by Barry Gordon) and Chance "T-Bone" Furlong (voiced by Charlie Adler) were members of Megakat City's paramilitary law enforcement agency, known as the Enforcers. They were dishonorably discharged from the Enforcers after disobeying the orders of Commander Feral (voiced by Gary Owens), which resulted in the destruction of the newly built Enforcer Headquarters. While in pursuit of the criminal mastermind Dark Kat (voiced by Brock Peters), one of the main arch-villains of the series, the two rebelled against Enforcer Commander Feral's orders to fall back and leave Dark Kat to him, as Feral wanted the honor and fame of bringing Dark Kat in personally as the leader of the Enforcers. When they objected, citing their already-acquired target lock, Commander Feral crowded out their jet, clipping their wing and sending Jake and Chance's jet crashing into Enforcer Headquarters. The resultant explosion distracted Commander Feral, allowing Dark Kat's escape. The Commander took no responsibility for the incident and damage to his own agency's new HQ, discharged Jake and Chance from the Enforcers when they tried to argue over who was to blame, and reassigned them to work at the city's military salvage yard to pay for the damage to the Enforcer Headquarters which Feral caused.

Using discarded military parts and weapons from the salvage yard, Jake and Chance built themselves a three-engine jet fighter called the Turbokat, which resembled several different jet fighters, most notably the Grumman F-14 and the Saab Draken, along with a handful of other vehicles such as the Cyclotron (a motorcycle built into the jet's seating, deployed from the bomb bay of the Turbokat like a missile), the TurboMole (a subterranean vehicle used to drill underground), the HoverKat (a militarized hovercraft), and the Thunder Truck (a militarized Jeep modified from their tow truck). All these vehicles were stored, along with a training area and other equipment, in a secret hangar below the yard.

Razor and T-Bone now patrol Megakat City as the SWAT Kats, defending it against any kind of menace that threatens the city. Their enemies include Dark Kat, the undead sorcerer Pastmaster (voiced by Keene Curtis), the mutant evil genius Doctor Viper (voiced by Frank Welker), and the robotic gangsters the Metallikats, husband and wife Mac and Molly Mange (voiced by Neil Ross and April Winchell). The SWAT Kats also face many villains-of-the-week, such as Rex Shard (voiced by John Vernon), Madkat (voiced by Roddy McDowall), Dr. Harley Street (voiced by Robert Ridgely), and Volcanus (vocal effects provided by Frank Welker).

The SWAT Kats keep their identities secret from everyone, including their closest ally Deputy Mayor Callie Briggs (voiced by Tress MacNeille), who assumes the responsibilities of both her post and of her boss, Mayor Manx (voiced by Jim Cummings), who mainly neglects his political duties in favor of pastimes like golf. Their methods do not endear them to Commander Feral, and the three of them often clash throughout the series.

In the second season, Feral's niece Felina (voiced by Lori Alan), who holds a lieutenant rank in the Enforcers, becomes another ally of the SWAT Kats.