Saint-Colomban (French pronunciation: [sɛ̃ kɔlɔ̃bɑ̃] ^ⓘ) is a city in the regional county municipality of La Rivière-du-Nord in Québec, Canada. It is situated in the Laurentides region of Québec and was named in honour of Saint Columbanus.

The pioneer responsible for developing the village was the priest John Falvey, who constructed the parish and preached to the first parishioners.

Saint-Colomban was also the birthplace of Mr. Justice Emmett Hall, a justice of the Supreme Court of Canada widely considered to be one of the fathers of Medicare.

The first European settlers arrived in Saint-Colomban in 1819 and the municipality of Saint-Colomban was officially founded in 1855. In 1857, part of Saint-Colomban was amputated to create the municipality of Saint-Canut (now part of Mirabel).

In 2009 Saint-Colomban's status was changed from a parish municipality to a regular municipality. One year later, in 2010, Saint-Colomban gained city status.

In the 2021 Census of Population conducted by Statistics Canada, Saint-Colomban had a population of 17,740 living in 6,632 of its 6,807 total private dwellings, a change of 10.7% from its 2016 population of 16,019. With a land area of 92.71 km² (35.80 sq mi), it had a population density of 191.3/km² (495.6/sq mi) in 2021.

The Commission scolaire de la Rivière-du-Nord operates French-language public schools.

The Sir Wilfrid Laurier School Board operates English-language public schools: