Paulson was in a relationship with actor and playwright Tracy Letts. They were engaged but ultimately did not marry.

Paulson was in a relationship with actress Cherry Jones, whom she met while working on a play. This relationship was significant as it marked Paulson's first public relationship with a woman. It ended amicably.

Paulson has been in a relationship with actress Holland Taylor since 2015. Their relationship has attracted considerable media attention due to the age difference. Paulson has been vocal about her love and respect for Taylor, and they have become a prominent and admired LGBTQ+ couple.

Paulson has been an outspoken advocate for LGBTQ+ rights and visibility. Her public relationships and her support for various LGBTQ+ organizations have contributed to greater representation and understanding.