St Lawrence is a rural town and locality in the Isaac Region, Queensland, Australia. In the 2021 census, the locality of St Lawrence had a population of 245 people.

St Lawrence is located 802 kilometres (498 mi) north of Brisbane and 6 kilometres (3.7 mi) off the Bruce Highway.The town is located south of St Lawrence Creek, which flows into a vast bay known as Broad Sound, a waterway noted for its large tidal range (up to 9 metres (30 ft) in the summer).

The North Coast railway line passes through the town, which is served by St Lawrence railway station.

Newport is a neighbourhood within the locality, about 5 kilometres (3.1 mi) south-east of the town (22°22′07″S 149°33′57″E / 22.3686°S 149.5658°E / -22.3686; 149.5658 (Newport)).

St Lawrence is located on Koinmerburra Country; the Custodians of this land are the Koinjmal People.

British settlement in the area began circa 1860 when John Arthur Macartney established Waverley pastoral station. The township of St Lawrence was originally established to maintain the Customs Office for the Port of St Lawrence. It takes its name from one of the blocks on the Waverley pastoral station.

The St Lawrence State School opened on 28 May 1871.

Anglican services were held quarterly in the St Lawrence Courthouse (now the St Lawrence Police Station) until the opening of the meatworks in 1893 attracted sufficient residents to establish a church. In March 1898, Vicar Arthur Henry Julius purchased 5 acres (2.0 ha) of land at the end of Macartney Street (the main street through the town) where he said the church would be "conspicuous". The foundation block for Christ Church Anglican was laid on Saturday 21 May 1898 by Thomas Byrnes, the new Queensland Premier (and Queensland's first Roman Catholic Premier). The church was designed by Rockhampton architect, Alfred Mowbray Hutton, to seat around 100 people with a classroom for Sunday School and a bedroom for visiting clergy. The contractors were Newman Bros of Rockhampton.