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Sterling Drug
Sterling Drug was an American based global pharmaceutical company. It was also known as Sterling Winthrop, Inc., after the merger with Winthrop-Stearns Inc. which itself resulted from the merger of Winthrop Chemical Company Inc. and Frederick Stearns & Company. It was formerly known as Sterling Winthrop Pharmaceuticals.
Primary product lines included diagnostic imaging agents, hormonal products, cardiovascular products, analgesics, antihistamines and muscle relaxants.
Chemical compounds produced by this company were often known by their manufacturing code which consisted of the abbreviation WIN (for Winthrop) followed by a number. For example, WIN 18,320 was nalidixic acid, the first quinolone antibiotic.
The Company was established in 1901 (then called Neuralgyline Co.) in Wheeling, West Virginia, by Albert H. Diebold and William E. Weiss, a pharmacist.[citation needed] At the end of World War I in 1918, Sterling purchased the US assets of a German company now known as Bayer AG for US$5.3 million. This purchase was directed under the Alien Property Custodian Act. In 1919, Sterling sold its dye division for $2.5 million to the Grasselli Chemical Company (based in Linden, New Jersey), which employed many former Bayer personnel.
A 1920 agreement between Sterling and Bayer was about selling aspirin in the Latin American markets: the profit would be shared fifty-fifty, with Bayer supplying the pharmaceutical and selling mainly via Sterlings salesmen. In 1923, another momentous contract was negotiated: 50% of the profits earned by Sterling's subsidiary Winthrop Chemical, was given to the German Bayer company, which in turn granted licences for new drugs and supported with technical expertise how to produce them. Later, this was turned into a 50% share in ownership. The American Bayer, owned by Sterling, retained the rights to use the "Bayer" brand for selling aspirin in the US, the UK and the Commonwealth. In 1923 Sterling purchased a 25% interest in The Centaur Company, manufacturer of Charles Henry Fletcher's, Fletcher's Castoria.
In 1940, a cross-contamination from equipment sharing resulted in Winthrop Chemical producing contaminated sulfathiazole tablets contaminated with phenobarbital. Each sulfathiazole tablet was contaminated with about 350 mg of phenobarbital. An investigation by US Food and Drug Administration and the findings resulted in actions. The incident was influential in the introduction of Good Manufacturing Practices for drugs.
Mollé Mystery Theatre was a 30-minute anthology radio program that ran from 1943 to 1948 on NBC prior to its moving to the CBS network. The show, sponsored initially by Sterling Drugs, manufacturers of Mollé Brushless Shaving Cream, began airing on Tuesday evenings during prime time. In 1948, Mollé ceased sponsoring the program, and its title became Mystery Theater.
In 1967, Sterling Drug acquired Lehn & Fink, the makers of Lysol, Resolve, and d-CON. In 1974, Sterling opened a manufacturing plant in McPherson, Kansas and Aurora, Ontario. The various companies which would eventually acquire Sterling chose to keep the factory open.[citation needed]
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Sterling Drug
Sterling Drug was an American based global pharmaceutical company. It was also known as Sterling Winthrop, Inc., after the merger with Winthrop-Stearns Inc. which itself resulted from the merger of Winthrop Chemical Company Inc. and Frederick Stearns & Company. It was formerly known as Sterling Winthrop Pharmaceuticals.
Primary product lines included diagnostic imaging agents, hormonal products, cardiovascular products, analgesics, antihistamines and muscle relaxants.
Chemical compounds produced by this company were often known by their manufacturing code which consisted of the abbreviation WIN (for Winthrop) followed by a number. For example, WIN 18,320 was nalidixic acid, the first quinolone antibiotic.
The Company was established in 1901 (then called Neuralgyline Co.) in Wheeling, West Virginia, by Albert H. Diebold and William E. Weiss, a pharmacist.[citation needed] At the end of World War I in 1918, Sterling purchased the US assets of a German company now known as Bayer AG for US$5.3 million. This purchase was directed under the Alien Property Custodian Act. In 1919, Sterling sold its dye division for $2.5 million to the Grasselli Chemical Company (based in Linden, New Jersey), which employed many former Bayer personnel.
A 1920 agreement between Sterling and Bayer was about selling aspirin in the Latin American markets: the profit would be shared fifty-fifty, with Bayer supplying the pharmaceutical and selling mainly via Sterlings salesmen. In 1923, another momentous contract was negotiated: 50% of the profits earned by Sterling's subsidiary Winthrop Chemical, was given to the German Bayer company, which in turn granted licences for new drugs and supported with technical expertise how to produce them. Later, this was turned into a 50% share in ownership. The American Bayer, owned by Sterling, retained the rights to use the "Bayer" brand for selling aspirin in the US, the UK and the Commonwealth. In 1923 Sterling purchased a 25% interest in The Centaur Company, manufacturer of Charles Henry Fletcher's, Fletcher's Castoria.
In 1940, a cross-contamination from equipment sharing resulted in Winthrop Chemical producing contaminated sulfathiazole tablets contaminated with phenobarbital. Each sulfathiazole tablet was contaminated with about 350 mg of phenobarbital. An investigation by US Food and Drug Administration and the findings resulted in actions. The incident was influential in the introduction of Good Manufacturing Practices for drugs.
Mollé Mystery Theatre was a 30-minute anthology radio program that ran from 1943 to 1948 on NBC prior to its moving to the CBS network. The show, sponsored initially by Sterling Drugs, manufacturers of Mollé Brushless Shaving Cream, began airing on Tuesday evenings during prime time. In 1948, Mollé ceased sponsoring the program, and its title became Mystery Theater.
In 1967, Sterling Drug acquired Lehn & Fink, the makers of Lysol, Resolve, and d-CON. In 1974, Sterling opened a manufacturing plant in McPherson, Kansas and Aurora, Ontario. The various companies which would eventually acquire Sterling chose to keep the factory open.[citation needed]