Synchronization is the coordination of events to operate a system in unison. For example, the conductor of an orchestra keeps the orchestra synchronized or in time. Systems that operate with all parts in synchrony are said to be synchronous or in sync—and those that are not are asynchronous.

Today, time synchronization can occur between systems around the world through satellite navigation signals and other time and frequency transfer techniques.

Time-keeping and synchronization of clocks is a critical problem in long-distance ocean navigation. Before radio navigation and satellite-based navigation, navigators required accurate time in conjunction with astronomical observations to determine how far east or west their vessel traveled. The invention of an accurate marine chronometer revolutionized marine navigation. By the end of the 19th century, important ports provided time signals in the form of a signal gun, flag, or dropping time ball so that mariners could check and correct their chronometers for error.

Synchronization was important in the operation of 19th-century railways, these being the first major means of transport fast enough for differences in local mean time between nearby towns to be noticeable. Each line handled the problem by synchronizing all its stations to headquarters as a standard railway time. In some territories, companies shared a single railroad track and needed to avoid collisions. The need for strict timekeeping led the companies to settle on one standard, and civil authorities eventually abandoned local mean time in favor of railway time.

In electrical engineering terms, for digital logic and data transfer, a synchronous circuit requires a clock signal. A clock signal simply signals the start or end of some time period, often measured in microseconds or nanoseconds, that has an arbitrary relationship to any other system of measurement of the passage of minutes, hours, and days.

In a different sense, electronic systems are sometimes synchronized to make events at points far apart appear simultaneous or near-simultaneous from a certain perspective. Timekeeping technologies such as the GPS satellites and Network Time Protocol (NTP) provide real-time access to a close approximation to the UTC timescale and are used for many terrestrial synchronization applications of this kind.

In computer science (especially parallel computing), synchronization is the coordination of simultaneous threads or processes to complete a task with correct runtime order and no unexpected race conditions; see synchronization (computer science) for details.

Synchronization is also an important concept in the following fields: