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Tankyrase 2
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Tankyrase-2 is an enzyme that in humans is encoded by the TNKS2 gene.[5]
Interactions
[edit]TNKS2 has been shown to interact with GRB14,[6] TERF1[7][8][9] and Cystinyl aminopeptidase.[8][9][10]
References
[edit]- ^ a b c GRCh38: Ensembl release 89: ENSG00000107854 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024811 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2".
- ^ Lyons RJ, Deane R, Lynch D K, Ye Z S, Sanderson G M, Eyre H J, Sutherland G R, Daly R J (May 2001). "Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14". J. Biol. Chem. 276 (20). United States: 17172–80. doi:10.1074/jbc.M009756200. ISSN 0021-9258. PMID 11278563.
- ^ Cook BD, Dynek Jasmin N, Chang William, Shostak Grigoriy, Smith Susan (January 2002). "Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres". Mol. Cell. Biol. 22 (1). United States: 332–42. doi:10.1128/MCB.22.1.332-342.2002. ISSN 0270-7306. PMC 134233. PMID 11739745.
- ^ a b Chi NW, Lodish H F (Dec 2000). "Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles". J. Biol. Chem. 275 (49). UNITED STATES: 38437–44. doi:10.1074/jbc.M007635200. ISSN 0021-9258. PMID 10988299.
- ^ a b Sbodio JI, Lodish Harvey F, Chi Nai-Wen (February 2002). "Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase)". Biochem. J. 361 (Pt 3). England: 451–9. doi:10.1042/0264-6021:3610451. ISSN 0264-6021. PMC 1222327. PMID 11802774.
- ^ Sbodio JI, Chi Nai-Wen (August 2002). "Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner". J. Biol. Chem. 277 (35). United States: 31887–92. doi:10.1074/jbc.M203916200. ISSN 0021-9258. PMID 12080061.
Further reading
[edit]- Monz D, Munnia A, Comtesse N, et al. (2001). "Novel tankyrase-related gene detected with meningioma-specific sera". Clin. Cancer Res. 7 (1): 113–9. PMID 11205898.
- Lyons RJ, Deane R, Lynch DK, et al. (2001). "Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14". J. Biol. Chem. 276 (20): 17172–80. doi:10.1074/jbc.M009756200. PMID 11278563.
- Kuimov AN, Kuprash DV, Petrov VN, et al. (2001). "Cloning and characterization of TNKL, a member of tankyrase gene family". Genes Immun. 2 (1): 52–5. doi:10.1038/sj.gene.6363722. PMID 11294570. S2CID 21519595.
- Kaminker PG, Kim SH, Taylor RD, et al. (2001). "TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression". J. Biol. Chem. 276 (38): 35891–9. doi:10.1074/jbc.M105968200. PMID 11454873.
- Cook BD, Dynek JN, Chang W, et al. (2002). "Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres". Mol. Cell. Biol. 22 (1): 332–42. doi:10.1128/MCB.22.1.332-342.2002. PMC 134233. PMID 11739745.
- Sbodio JI, Lodish HF, Chi NW (2002). "Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase)". Biochem. J. 361 (Pt 3): 451–9. doi:10.1042/0264-6021:3610451. PMC 1222327. PMID 11802774.
- Seimiya H, Smith S (2002). "The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)". J. Biol. Chem. 277 (16): 14116–26. doi:10.1074/jbc.M112266200. PMID 11854288.
- Sbodio JI, Chi NW (2002). "Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner". J. Biol. Chem. 277 (35): 31887–92. doi:10.1074/jbc.M203916200. PMID 12080061.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
- Deng Z, Atanasiu C, Zhao K, et al. (2005). "Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1". J. Virol. 79 (8): 4640–50. doi:10.1128/JVI.79.8.4640-4650.2005. PMC 1069541. PMID 15795250.
- Sidorova N, Zavalishina L, Kurchashova S, et al. (2006). "Immunohistochemical detection of tankyrase 2 in human breast tumors and normal renal tissue". Cell Tissue Res. 323 (1): 137–45. doi:10.1007/s00441-005-0053-8. PMID 16151859. S2CID 21992320.
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