The Invisible Man (also shortened to "The I-Man" in Season 2) is an American science fiction television series starring Vincent Ventresca, Paul Ben-Victor, Eddie Jones, Shannon Kenny and Michael McCafferty.

The show aired two seasons, from June 9, 2000, to February 1, 2002, on the Sci Fi Channel and was syndicated to American TV stations. It was cancelled by USA Cable Entertainment, Sci Fi's parent company, primarily due to the high production costs of visual effects. For some episodes, budgets went over $1 million. Falling viewership meant advertising revenue was unable to support the high costs.

The series uses elements of science fiction and action to explore themes such as freedom of choice, determinism, and state bureaucracy.

The Invisible Man is both an action show and a comedy with buddy cop elements.

The plot revolves around Darien Fawkes (Ventresca), a thief facing life imprisonment who is recruited by a spy agency that is constantly short on funds, and is given the power of invisibility via implantation of a special "Quicksilver gland" in his head. The gland allows Fawkes to secrete a light-bending substance called "Quicksilver" from his pores and follicles. The substance quickly coats his skin, hair, nails, clothes, and whatever he is carrying, and renders him invisible. He can consciously release the Quicksilver, which then flakes off and disintegrates. However, the Quicksilver gland was sabotaged at its creation by scientist Arnaud DeFehrn to release a neurotoxin that accumulates in the bloodstream and causes intense pain, followed by antisocial behavior and psychosis. The host requires regular doses of "counteragent" to keep him sane and healthy, which is controlled by the government agency.

There were typically two types of episodes. Many of these were cases that The Agency had provided to Fawkes and Hobbes. These mostly dealt with murders or government experiments gone wrong. Chrysalis, The Agency's enemy agency from the first season, was frequently responsible for the week's plot. Episodes instead focused on Fawkes' struggle to have the organ removed from his skull and/or lessen his dependence on the counteragent. His unconventional means included using his deceased brother's intellect to revive him and occasionally speaking with Arnaud DeFehrn, one of the gland's inventors, albeit these interactions typically ended with one of them being in pain. Since the agency believed that the gland was too valuable to be taken away, Fawkes' personal pursuit frequently put him at odds with those in positions of power.

Episodes usually begin with a voice-over by Fawkes who would open with a famous quote and comment about what he was currently thinking. The voice over would reemerge at the end of the episode to sum up Fawkes' opinion on the mission or allow him to voice lingering questions.

At the conclusion of the series, Fawkes had been given a new counteragent that permanently cured him of quicksilver madness — his body having become gradually immune to the standard counteragent — but after briefly returning to his old thieving career and another stint at the FBI, he returned to the Agency to continue fighting Chrysalis.