Thomas Midgley Jr. was born in Beaver Falls, Pennsylvania, to Thomas Midgley Sr. and Hattie L. Emerson. His father was an inventor, and his grandfather, James Emerson, was a renowned mechanical engineer, providing an early exposure to science and invention.

Growing up, Midgley was encouraged to explore his mechanical aptitude and scientific curiosity. His father's inventions likely sparked an interest in engineering and problem-solving.

Midgley attended Cornell University, where he studied mechanical engineering. This education provided him with the foundational knowledge and skills necessary for his future work in chemistry and engineering at General Motors.

Midgley graduated from Cornell University with a degree in mechanical engineering. Following graduation, he briefly worked in various jobs to gain practical experience.