Tirupathur district is one of the 38 districts in the southern Indian state of Tamil Nadu. The district was formed in 2019 by the division of Vellore district into three smaller districts. Its creation alongside Ranipet district was announced on 15 August 2019, and it was officially declared on 28 November 2019. The town of Thiruppathur serves as the district headquarters.

The district is bordered by Vellore district to the northeast, Krishnagiri district to the southwest, Thiruvannamalai district to the southeast, and the Chittoor district of Andhra Pradesh to the northwest. National Highway 48 passes through the district.

Tirupattur district was created by the splitting off of the three southwestern taluks of Vellore district: Thirupathur, Vaniyambadi, and Ambur. The district now includes Naatrampalli for a total of four taluks.

Thirupathur Revenue Division: Thirupathur, Natrampalli

Vaniyambadi Revenue Division: Vaniyambadi, Ambur

Proposed Taluks: Jolarpettai, Alangayam

Proposed Municipalities: Naatrampalli, Alangayam

Proposed Town Panchayats: Kandhili, Madhanur, Jaffrabad, Thuthipattu, Kailasagiri, Pachchal, Valayambattu