The Microbicide Trials Network (MTN, 2006-2021) was a United States government-funded research organization working in the field of microbicides for sexually transmitted diseases.[1][2] The MTN focused on research into microbicides which would prevent HIV infection. The MTN was a member of HANC. After its closure, partner organization HIV Prevention Trials Network took control of its projects.[2]
The MTN's notable research included various clinical trials.
The results of the CAPRISA 004 trial inspired the research of the MTN and the microbicide field.[3]
The Vaginal and Oral Interventions to Control the Epidemic (VOICE) found a vaginal gel containing an anti-HIV drug to be ineffective at preventing HIV transmission..[4]
The HOPE study tested dapivirine vaginal rings for HIV prevention in 1,456 study participants at 14 sites in Malawi, South Africa, Uganda and Zimbabwe.[5]
