The fighting game genre involves combat between characters, often (but not necessarily limited to) one-on-one battles. The mechanics of combat in fighting games often features blocking, grappling, counter-attacking, and the ability to chain attacks together into "combos". Characters generally engage in hand-to-hand combat, often incorporating martial arts, but some may include weaponry. Battles are usually set in a fixed-size arena along a two-dimensional plane, where characters navigate horizontally by walking or dashing, and vertically by jumping. Some games allow limited movement in 3D space, such as Tekken and Soul Edge while some are set in fully three-dimensional environments without restricting characters' movement, such as Dragon Ball Z: Budokai Tenkaichi, Jump Force, Kill la Kill: If, My Hero: One's Justice, Naruto: Ultimate Ninja Storm, One Piece: Burning Blood and Power Stone; these are sometimes referred to as "3D arena" fighting games.

The fighting game genre is distinctly related to the beat 'em up genre, which pits many computer-controlled enemies against one or more player characters. The first video game to feature fist fighting is Heavyweight Champ (1976), but Karate Champ (1984) actually features the one-on-one fighting game genre instead of a sports game in arcades. Yie Ar Kung-Fu was released later that year with various fighting styles and introduced health meters, and The Way of the Exploding Fist (1985) further popularized the genre on home systems. In 1987, Capcom's Street Fighter introduced special attacks, and in 1991, its highly successful sequel Street Fighter II refined and popularized many genre conventions, including combos. Fighting games subsequently became the preeminent genre for video gaming in the early to mid-1990s, particularly in arcades. This period spawned dozens of other popular fighting games, including franchises like Street Fighter, Mortal Kombat, Super Smash Bros., and Tekken.

Fighting games are a type of action game where two (in one-on-one fighting games) or more (in platform fighters) on-screen characters fight each other. These games typically feature special moves that are triggered using rapid sequences of carefully timed button presses and joystick movements. Games traditionally show fighters from a side view, even as the genre has progressed from two-dimensional (2D) to three-dimensional (3D) graphics. Street Fighter II, though not the first fighting game, is considered to have standardized the genre, and similar games released prior to Street Fighter II have since been more explicitly classified as fighting games. Fighting games typically involve hand-to-hand combat, though many games also feature characters with melee weapons. Fighting characters are usually based on humans, but there are also games that are entirely based around mecha robot characters, for example the Gundam: Battle Assault series.

This genre is distinctly related to beat 'em ups, another action genre involving combat, where the player character must fight many enemies at the same time. Beat 'em ups, like traditional fighting games, display player and enemy health in a bar, generally located at the top of the screen. However, beat 'em ups generally do not feature combat divided into separate "rounds". During the 1980s to 1990s, publications used the terms "fighting game" and "beat 'em up" interchangeably, along with other terms such as "martial arts simulation" (or more specific terms such as "judo simulator") and "punch-kick" games. Fighting games were still being called "beat 'em up" games in video game magazines up until the end of the 1990s. With hindsight, critics have argued that the two types of game gradually became dichotomous as they evolved, though the two terms may still be conflated.

Sports-based combat games are games that feature boxing, mixed martial arts (MMA), or wrestling. Serious boxing games belong more to the sports game genre than the action game genre, as they aim for a more realistic model of boxing techniques, whereas moves in fighting games tend to be either highly exaggerated or outright fantastical models of Asian martial arts techniques. As such, boxing games, mixed martial arts games, and wrestling games are often described as distinct genres, without comparison to fighting games, and belong more in the sports game genre.

Fighting games involve combat between pairs of fighters using highly exaggerated martial arts moves. They typically revolve primarily around brawling or combat sport, though some variations feature weaponry. Games usually display on-screen fighters from a side view, and even 3D fighting games play largely within a 2D plane of motion. Games usually confine characters to moving left and right and jumping, although some games such as Fatal Fury: King of Fighters allow players to move between parallel planes of movement. Recent games tend to be rendered in three dimensions, making it easier for developers to add a greater number of animations, but otherwise play like those rendered in two dimensions. Games that are fully three-dimensional without a 2D plane are sometimes referred to as "3D arena" fighting games.

Aside from restricting movement space, fighting games confine the player's actions to offensive and defensive maneuvers. Players must learn each game's effective combinations of attacks and defenses. Blocking is a basic defense against basic attacks. Some games feature more advanced blocking techniques; for example, Capcom's Street Fighter III features a move termed "parrying", which can be immediately followed by counter-attack, skipping the temporary stun a block would have put them in. A similar stun state is termed "just defended" in SNK's Garou: Mark of the Wolves.

An integral feature of fighting games is the use of "special attacks", also called "secret moves", that employ combinations of directional inputs and button presses to perform a particular move beyond basic punching and kicking. Some special moves, which play an animation portraying an aspect of the character's personality, are referred to as taunts. Originated by Japanese company SNK in Art of Fighting (1992), these add humor, and they affect gameplay in certain games, such as improving the strength of other attacks. Some characters have unusual taunts, like Dan Hibiki from Street Fighter Alpha.