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Hub AI
Visceral pain AI simulator
(@Visceral pain_simulator)
Hub AI
Visceral pain AI simulator
(@Visceral pain_simulator)
Visceral pain
Visceral pain is defined as pain that results from the activation of nociceptors of the thoracic, pelvic, or abdominal viscera (organs) in the human body. Visceral structures are highly sensitive to distension (stretch), ischemia and inflammation, but relatively insensitive to other stimuli that normally evoke pain such as cutting or burning.
Visceral pain is diffuse, difficult to localize, and often referred to a distant, usually superficial, structure. It may be accompanied by symptoms such as nausea, vomiting, changes in vital signs as well as emotional manifestations. The pain may be described as sickening, throbbing, pulsating, deep, squeezing, and/or dull.
Nociceptive innervation is often the only type of sensory innervation possessed by visceral structures. Nociceptive innervation of visceral structures entails two distinct modalities:
When both visceral and parietal nociceptors are activated, both pain modalities will be perceived simultaneously (for example, appendicitis may be associated with dull visceral pain at the level of the umbilicus (T10-T11) as well as sharp parietal pain at the lower right quadrant of the abomen).
The liver parenchyma and lung alveoli are virtually free of nociceptive innervation; nevertheless, bile ducts and the connective tissue covering of the liver are sensitive to pain, as are the bronchi and parietal pleura.
Visceral pain may be evoked by:
Inflammation, or repetitive or prolongued exposure to non-noxious stimuli may render viscera hyperalgesic, lowering the pain threshold of affected viscera. For example, repetitive experimental filling of the distal colon of human subjects initially produces distension that is perceived as painless, but the same distension subsequently comes to be experienced as painful. Such hyperalgesia may underlie pain experienced in certain clinical conditions like inflammatory bowel disease and may thus also represent a therapeutic target.
Visceral pain is one of the main presenting complaints of patients and is frequently encountered in the clinical setting. True visceral pain.
Visceral pain
Visceral pain is defined as pain that results from the activation of nociceptors of the thoracic, pelvic, or abdominal viscera (organs) in the human body. Visceral structures are highly sensitive to distension (stretch), ischemia and inflammation, but relatively insensitive to other stimuli that normally evoke pain such as cutting or burning.
Visceral pain is diffuse, difficult to localize, and often referred to a distant, usually superficial, structure. It may be accompanied by symptoms such as nausea, vomiting, changes in vital signs as well as emotional manifestations. The pain may be described as sickening, throbbing, pulsating, deep, squeezing, and/or dull.
Nociceptive innervation is often the only type of sensory innervation possessed by visceral structures. Nociceptive innervation of visceral structures entails two distinct modalities:
When both visceral and parietal nociceptors are activated, both pain modalities will be perceived simultaneously (for example, appendicitis may be associated with dull visceral pain at the level of the umbilicus (T10-T11) as well as sharp parietal pain at the lower right quadrant of the abomen).
The liver parenchyma and lung alveoli are virtually free of nociceptive innervation; nevertheless, bile ducts and the connective tissue covering of the liver are sensitive to pain, as are the bronchi and parietal pleura.
Visceral pain may be evoked by:
Inflammation, or repetitive or prolongued exposure to non-noxious stimuli may render viscera hyperalgesic, lowering the pain threshold of affected viscera. For example, repetitive experimental filling of the distal colon of human subjects initially produces distension that is perceived as painless, but the same distension subsequently comes to be experienced as painful. Such hyperalgesia may underlie pain experienced in certain clinical conditions like inflammatory bowel disease and may thus also represent a therapeutic target.
Visceral pain is one of the main presenting complaints of patients and is frequently encountered in the clinical setting. True visceral pain.