Wayland is a town in Middlesex County, Massachusetts, United States. The town was founded in 1638, and incorporated in 1780 and was originally part of neighboring Sudbury (incorporated 1639). At the 2020 United States census, the population was 13,943. It contains the census-designated place of Cochituate.

Wayland was the first settlement of Sudbury Plantation in 1638. The residents of what is now Sudbury split away in 1722 and formed into the western parish, while residents of what is now Wayland formed into the eastern parish. Prior to the American Revolution Sudbury had one of the largest militias in Massachusetts, numbering about 400. During the Battles of Lexington and Concord on April 19, 1775, approximately 302 members of the Sudbury militia, including 115 from the eastern parish, marched to Concord.

The Town of East Sudbury split away from the western parish and was formally incorporated on April 10, 1780. "The higher average wealth level of the residents on the eastern side of the river and on Pelham Island caused the east side of Town to have a higher total assessment than the west side... the east-siders paid more than half of Town taxes even though more than half of the Town population (and the associated costs for Town services) was on the west side."

On March 11, 1835, members of town meeting voted to rename East Sudbury "Wayland" in honor of Dr. Francis Wayland, who was a temperance advocate, abolitionist, then president of Brown University, and a friend of local Judge Edward Mellen. Both Wayland and Mellen were strong advocates of public libraries, and donated money to fund the establishment of a public library for the town. When questions arose about the legality of taxing residents to establish a library, Representative Reverend John Burt Wight brought the question to the state legislature, which led to an 1851 Massachusetts state law enabling the establishment of free public libraries. This makes the Wayland Public library arguably the first free public library in the state and the second public library in the country. The current library building was built in 1900.

Famous residents of Wayland in the mid-19th century include abolitionist Rev. Edmund Sears, the minister of the First Parish Church, who wrote the 1849 poem and song "It Came Upon the Midnight Clear" and abolitionist, author, and suffragist Lydia Maria Child.

The Sudbury Valley Trustees were founded in 1953 by seven men from Wayland.

In 1954, during the Red Scare, elementary school teacher Anne Hale was fired in a 2–1 vote by the Wayland School Committee. She had been a member of the Communist Party from 1938 to 1950 and the committee members who voted to fire her stated her lack of "perception, understanding, and judgment necessary in one who is to be entrusted with the responsibility for teaching the children of the Town."

In 2010, Boston Duck Tours was asked to help transport flood victims in Wayland. Torrential rains had left the Pelham Island area of Wayland isolated and the Ducks were brought in to ferry people in and out of their neighborhood until the waters receded.