WormBook
View on WikipediaWormBook is an open access, comprehensive collection of original, peer-reviewed chapters covering topics related to the biology of the nematode worm Caenorhabditis elegans (C. elegans). WormBook also includes WormMethods, an up-to-date collection of methods and protocols for C. elegans researchers.[1][2][3][4]
Key Information
WormBook is the online text companion to WormBase,[5] the C. elegans model organism database. Capitalizing on the World Wide Web, WormBook links in-text references (e.g. genes, alleles, proteins, literature citations) with primary biological databases such as WormBase and PubMed. C. elegans was the first multicellular organism to have its genome sequenced[6] and is a model organism for studying developmental genetics and neurobiology.
Contents
[edit]The content of WormBook is categorized into the sections listed below, each filled with a variety of relevant chapters. These sections include:
- Genetics and genomics[7]
- Molecular biology
- Biochemistry
- Cell Biology
- Signal transduction[8]
- Developmental biology
- Post-embryonic development
- Sex-determination systems[9]
- The germ line[10]
- Neurobiology and behavior
- Evolution and ecology[11]
- Disease models and drug discovery
- WormMethods
References
[edit]- ^ "The WormBook website". wormbook.org.
- ^ White, John Graham (2013). "Getting into the mind of a worm—a personal view". WormBook: 1–10. doi:10.1895/wormbook.1.158.1. PMC 4781474. PMID 23801597.
- ^ Corsi, Ann K. (2015). "A Transparent window into biology: A primer on Caenorhabditis elegans". WormBook: 1–31. doi:10.1895/wormbook.1.177.1. ISSN 1551-8507. PMC 4781331. PMID 26087236.
- ^ Greenwald, I. (2016). "WormBook: WormBiology for the 21st Century". Genetics. 202 (3): 883–884. doi:10.1534/genetics.116.187575. ISSN 0016-6731. PMC 4788125. PMID 26953267.
- ^ Howe, Kevin L.; Bolt, Bruce J.; Cain, Scott; Chan, Juancarlos; Chen, Wen J.; Davis, Paul; Done, James; Down, Thomas; Gao, Sibyl; Grove, Christian; Harris, Todd W.; Kishore, Ranjana; Lee, Raymond; Lomax, Jane; Li, Yuling; Muller, Hans-Michael; Nakamura, Cecilia; Nuin, Paulo; Paulini, Michael; Raciti, Daniela; Schindelman, Gary; Stanley, Eleanor; Tuli, Mary Ann; Van Auken, Kimberly; Wang, Daniel; Wang, Xiaodong; Williams, Gary; Wright, Adam; Yook, Karen; Berriman, Matthew; Kersey, Paul; Schedl, Tim; Stein, Lincoln; Sternberg, Paul W. (2016). "WormBase 2016: expanding to enable helminth genomic research". Nucleic Acids Research. 44 (D1): D774 – D780. doi:10.1093/nar/gkv1217. PMC 4702863. PMID 26578572.
- ^ The C. elegans Sequencing Consortium (1998). "Genome sequence of the nematode C. elegans: A platform for investigating biology". Science. 282 (5396): 2012–2018. Bibcode:1998Sci...282.2012.. doi:10.1126/science.282.5396.2012. PMID 9851916.
- ^ Hodgkin, Jonathan (2005). "Introduction to genetics and genomics". WormBook. doi:10.1895/wormbook.1.17.1.
- ^ Greenwald, Iva (2005). "Introduction to signal transduction". WormBook. doi:10.1895/wormbook.1.20.1.
- ^ Herman, Robert (2005). "Introduction to sex determination". WormBook. doi:10.1895/wormbook.1.71.1.
- ^ Hubbard, E. Jane (2005). "Introduction to the germ line". WormBook: 1–4. doi:10.1895/wormbook.1.18.1. PMC 4781435. PMID 18050415.
- ^ Fitch, David H.A. (2005). "Introduction to nematode evolution and ecology". WormBook: 1–8. doi:10.1895/wormbook.1.19.1. PMC 4781023. PMID 18050395.
