The Xavier Musketeers men's soccer team is an intercollegiate varsity sports team of Xavier University. The team is a member of the Big East Conference of the National Collegiate Athletic Association.

Xavier University is a Jesuit university established in Cincinnati, Ohio in 1831. In March 1974, it was announced that a varsity soccer program would be formed at Xavier, and tryouts were held. Coached by Bob McKinney, the team played their first ever regular season match on September 21, 1974, at Corcoran Field, defeating the visiting Thomas More Rebels 3–2. They finished their inaugural fall season with a 5–7–0 record.

In 1975, the team brought in its first ever class of recruits, with McKinney scouting several players from nearby high school teams. They finished the 1975 season with an 8–5–0 record. However, after finishing 1976 with a 3–4–3 record, Bob McKinney resigned as head coach.

In March 1977, Xavier hired John Capurro as their new head coach. John Capurro had previously assisted his brother, Nick Capurro, in coaching the Cincinnati Comets, a short-lived professional team which had folded in 1975.

Vince Pecoraro took Capurro's place as head coach ahead of the 1986 season.

Until 1987, the Xavier men's soccer team had not been a part of any athletic conference. Xavier University had been a founding member of the Midwestern Collegiate Conference (MCC) since 1979, but the conference did not originally sponsor men's soccer. Xavier was one of six universities to play in the MCC's inaugural men's soccer season in 1987.

In 1991, Jack Hermans replaced Pecoraro as Xavier's new head coach.

In 1995, Xavier left the MCC and joined the Atlantic 10 Conference.