The 1928-29 Divisione Nazionale was the twenty-ninth edition of the Italian Football Championship. It was also the sixth season from which the Italian Football Champions adorned their team jerseys in the subsequent season with a Scudetto. This was the third of three seasons of the Italian Football Championship re-branded to Divisione Nazionale (prior to the fourth re-brand that in 1929 created Serie A and Serie B). The 1928–29 Divisione Nazionale was the second Italian Football Championship won by Bologna.

Divisione Nazionale was organised into two non-geographical round robin contests. In 1928-29 it was contested by 27 clubs from what was then within Northern Italy, plus three Central and two Southern Italian clubs. The top team from each of they two round robins then decided the championship via a two-legged final.

In 1928 the fascist regime allowed for 1929 the start of the Serie A they stopped in 1926, not before to readmit SS Lazio and SC Napoli to allow a wider representation of Southern Italy, and AS Livorno and La Dominante to avoid odd groups.

More, during the summer the FIGC decided another expansion of the championship to allow a wider representation of the territories annexed after WWI, to save the remaining two clubs of the closing season, and to include AC Fiorentina and three other minor clubs, effectively making the new tournament a mixed Serie A-Serie B championship that should split into the two leagues.

Both clubs were admitted to the Serie A to allow a wider representation of Southern Italy.

Italy was invited to join the 1929 Mitropa Cup when the championship was not yet finished, so the FIGC decided a playoff between the apparent runners-up Juventus and Milan, and two out of the three remaining football giants Inter and Genoa.

Because of the sole points were considered by the championship regulations, with no relevance to the aggregation of goals, a tie-break was needed.