| 1981 U.S. Pro Indoor | |
|---|---|
| Date | January 26 – February 1 |
| Edition | 14th |
| Category | Grand Prix circuit (WCT) |
| Draw | 48S / 24D |
| Prize money | $250,000 |
| Surface | Carpet / indoor |
| Location | Philadelphia, Pennsylvania, U.S. |
| Venue | Spectrum |
| Champions | |
| Singles | |
 Roscoe Tanner[1] | |
| Doubles | |
| Marty Riessen / Sherwood Stewart[2] | |
The 1981 U.S. Pro Indoor was a men's tennis tournament played on indoor carpet courts. It was a WCT tournament that was part of the 1981 Volvo Grand Prix circuit. The tournament was played at the Spectrum in Philadelphia, Pennsylvania in the United States and was held from January 26 through February 1, 1981. Seventh-seeded Roscoe Tanner won the singles title.
Roscoe Tanner defeated 
Wojciech Fibak 6–2, 7–6, 7–5
Marty Riessen / Sherwood Stewart defeated Brian Gottfried / 
Raúl Ramírez 6–2, 6–2
