2-APBT

2-APBT

Clinical data
Drug class	Serotonin–norepinephrine–dopamine releasing agent
ATC code	None
Identifiers
IUPAC name 1-(1-benzothiophen-2-yl)propan-2-amine
CAS Number	103861-05-8
PubChem CID	22463352
ChemSpider	13468670
Chemical and physical data
Formula	C11H13NS
Molar mass	191.29 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(CC1=CC2=CC=CC=C2S1)N
InChI InChI=1S/C11H13NS/c1-8(12)6-10-7-9-4-2-3-5-11(9)13-10/h2-5,7-8H,6,12H2,1H3 Key:LQRQTYOYXPEWJR-UHFFFAOYSA-N

2-APBT is a monoamine releasing agent (MRA) of the benzothiophene family.^[1][2] It acts specifically as a fairly well-balanced serotonin–norepinephrine–dopamine releasing agent (SNDRA), with EC₅₀Tooltip half-maximal effective concentration values of 8.9 nM for serotonin, 21.6 nM for norepinephrine, and 38.6 nM for dopamine in rat brain synaptosomes.^[2] 2-APBT was first described in the scientific literature by 2020.^[1][2]

• 2-APBT - Isomer Design

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