The 2006 Banka Koper Slovenia Open was a women's tennis tournament played on outdoor hard courts. It was the 2nd edition of the Slovenia Open, and was part of the WTA Tier IV tournaments of the 2006 women's professional tennis season. It was held in Portorož, Slovenia, from 18 September until 24 September 2006. Unseeded Tamira Paszek, who entered the competition as a qualifier, won the singles title.

Tamira Paszek defeated Maria Elena Camerin, 7–5, 6–1

Lucie Hradecká / Renata Voráčová claimed the title, when Eva Birnerová / Émilie Loit withdrew before the final.

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