The 2010 Australian motorcycle Grand Prix was the sixteenth round of the 2010 Grand Prix motorcycle racing season. It took place on the weekend of 15–17 October 2010 at the Phillip Island Grand Prix Circuit. Australian Casey Stoner won his fourth consecutive home race, which was also his last win for Ducati and Ducati's last win until the 2016 Austrian motorcycle Grand Prix.

Wayne Maxwell was black flagged for dangerous riding, crashing into Héctor Faubel during the first lap with a physical altercation following.

Below are the standings for the top five riders and constructors after round sixteen has concluded.