The 2011 Orlando Predators season was the 20th season for the franchise in the Arena Football League. The team was coached by Pat O'Hara. This was the Predators' first season at Amway Center. The Predators finished the regular season 11–7, qualifying for the playoffs for the 19th consecutive season. As the 4th seed in the American Conference, they lost to the Jacksonville Sharks in the conference semifinals, 48–63.

z - Clinched division and conference's best record
x - Clinched playoff berth

The Predators had a bye during Week 1, and began the season the following week on the road against the New Orleans VooDoo on March 18. They played their first game at Amway Center against the Utah Blaze on March 24. On July 23, they will host New Orleans for their final regular season game.

at New Orleans Arena, New Orleans, Louisiana

at Amway Center, Orlando, Florida

at US Airways Center, Phoenix, Arizona

at Amway Center, Orlando, Florida

at Arena at Gwinnett Center, Duluth, Georgia