The 2012 NCAA Division I baseball tournament began on Friday, June 1, 2012, as part of the 2012 NCAA Division I baseball season. The 64 team double elimination tournament concluded with the 2012 College World Series in Omaha, Nebraska, starting on June 15 and ending on June 25.

The 64 NCAA Division I college baseball teams were selected out of an eligible 297 teams. Thirty teams were awarded an automatic bid as champions of their conferences, and 34 teams were selected at-large by the NCAA Division I Baseball Committee.

Conference champions from 30 Division I conferences earned automatic bids to regionals. The remaining 34 spots were awarded to schools as at-large invitees.

These eight teams would automatically host a Super Regional had they advanced to that round. Only North Carolina failed to advance out of its regional.

Bold indicates CWS participant.

Bold indicates winner. * indicates extra innings.

†Purdue hosted at the U.S. Steel Yard in Gary, Indiana, due to the construction delays of the Boilermaker's new stadium, Alexander Field.

Seeds listed below indicate national seeds only.