The 2015 myAFibRisk.com 400 was a NASCAR Sprint Cup Series race held on September 20, 2015, at Chicagoland Speedway in Joliet, Illinois. Contested over 267 laps on the 1.5 mile (2.4 km) intermediate speedway, it was the 27th race of the 2015 NASCAR Sprint Cup Series season, first race of the Chase and first race of the Challenger Round. Denny Hamlin won the race, his second of the season. Carl Edwards finished second. Kurt Busch, Ryan Newman and Matt Kenseth rounded out the top–five.

Due to qualifying being rained-out, Kevin Harvick was given the first starting spot of the race. He led 10 laps before wrecking out halfway through the race and finished 42nd. Kyle Busch led a race high of 121 laps on his way to a ninth–place finish. There were 17 lead changes among 10 different drivers, as well as six caution flag periods for 28 laps.

This was Denny Hamlin's 26th career win, second of the season, first at Chicagoland Speedway and fifth at the track for Joe Gibbs Racing. The win moved Hamlin up to second in the points trailing teammate Matt Kenseth by two. Despite being the winning manufacturer, Toyota left Chicagoland trailing Chevrolet by 49–points in the manufacturer standings.

The myAFibRisk.com 400 was carried by NBC Sports on the cable/satellite NBCSN network for the American television audience. The radio broadcast for the race was carried by the Motor Racing Network and Sirius XM NASCAR Radio.

Chicagoland Speedway is a 1.5 miles (2.4 km) tri-oval speedway in Joliet, Illinois, southwest of Chicago. The speedway opened in 2001 and currently hosts NASCAR racing including the opening event in the Chase for the Sprint Cup. Until 2011, the speedway also hosted the IndyCar Series, recording numerous close finishes including the closest finish in IndyCar history. The speedway is owned and operated by International Speedway Corporation and located adjacent to Route 66 Raceway.

Jimmie Johnson entered Chicagoland tied with Kyle Busch and Matt Kenseth for the points lead at 2,012–points. Joey Logano entered three–points back. Kevin Harvick, Dale Earnhardt Jr., Kurt Busch and Carl Edwards entered tied for fifth six–points back. Brad Keselowski, Martin Truex Jr. and Denny Hamlin entered tied for ninth nine–points back. Jamie McMurray, Jeff Gordon, Ryan Newman, Paul Menard and Clint Bowyer entered tied for 12th 12–points back.

Following complaints of Matt Kenseth jumping the final restart at Richmond, NASCAR decided to add a camera feed and official with the sole purpose of monitoring the restart zone.

When the green flag flies on Sunday, Jeff Gordon – who made his first career Sprint Cup Series start in the 1992 Hooters 500 at what was then Atlanta International Raceway (now Atlanta Motor Speedway) – tied Ricky Rudd's record for most consecutive starts at 788. The 23–year veteran of the sport will break the tie next weekend at New Hampshire Motor Speedway. “I’ve got to get through this weekend first,” he said. “That’s one of those things where I feel a little strange talking about it because I do appreciate and respect the safety of this sport. (That) side can be taken away from you at any time. I want to break that record. I think it’s a huge accomplishment because it’s not easy to do. It’s easier today because the sport is safer. I look at Ricky Rudd and what he went through to make it. That is pretty extraordinary. I can’t quite compare that.”