| 2018 Città di Como Challenger | |
|---|---|
| Date | 27 August – 2 September |
| Edition | 13th |
| Surface | Clay |
| Location | Como, Italy |
| Champions | |
| Singles | |
 Salvatore Caruso | |
| Doubles | |
 Andre Begemann / Dustin Brown | |
The 2018 Città di Como Challenger was a professional tennis tournament played on clay courts. It was the thirteenth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Como, Italy between 27 August – 2 September 2018.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 SVK
|
Martin Kližan | 72 | 1 |
 BOL
|
Hugo Dellien | 105 | 2 |
 POR
|
Pedro Sousa | 115 | 3 |
 BRA
|
Thiago Monteiro | 119 | 4 |
 ARG
|
Juan Ignacio Londero | 123 | 5 |
 FRA
|
Stéphane Robert | 136 | 6 |
| POR
|
Gastão Elias | 147 | 7 |
| BRA
|
Rogério Dutra Silva | 151 | 8 |
The following players received wildcards into the singles main draw:
Filippo Baldi Alessandro Coppini Francesco Forti Jannik SinnerThe following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
Salvatore Caruso def. 
Christian Garín 7–5, 6–4. Andre Begemann / Dustin Brown def. Martin Kližan / Filip Polášek 3–6, 6–4, [10–5].
