The 2018 Fall United Premier Soccer League season is the 11th season of the UPSL. Milwaukee Bavarian SC are the reigning champions. However, the Midwest Conference will not participate in the fall season, and the Bavarians will not be able to defend their title.

For the Fall 2018 season, UPSL had 89 teams compete in 13 Pro Premier Divisions divided into 5 conferences. An additional 29 teams competed in 3 Championships Divisions from 2 Conferences. The overall structure of the League by Conference and roughly from west to east is represented in the table below

 * Not participating

Joined Heart Division

Rebranded

Teams are divided into five conferences, some of which are further subdivided into divisions. Unless specified otherwise, all playoff matches are contested over a single leg, hosted by the team with the best points-per-game ratio. Extra time is not used in any round; matches drawn after 90 minutes advance directly to a penalty shootout.

The match originally ended 5-1 in favor of San Juan FC, but they were subsequently ruled to have fielded an ineligible player. Boise Cutthroats FC was advanced to the next round.

The following 7 clubs joined the division for its inaugural season