| 2021 Trofeo Faip–Perrel | |
|---|---|
| Date | 1–7 November |
| Edition | 16th |
| Surface | Hard (Indoor) |
| Location | Bergamo, Italy |
| Champions | |
| Singles | |
 Holger Rune | |
| Doubles | |
 Zdeněk Kolář / Jiří Lehečka | |
The 2021 Trofeo Faip–Perrel was a professional tennis tournament played on hard courts. It was the sixteenth edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Bergamo, Italy between 1 and 7 November 2021.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 SVK
|
Alex Molčan | 114 | 1 |
 AUT
|
Dennis Novak | 116 | 2 |
| DEN
|
Holger Rune | 121 | 3 |
 MDA
|
Radu Albot | 123 | 4 |
 GBR
|
Liam Broady | 124 | 5 |
| CZE
|
Zdeněk Kolář | 138 | 6 |
 SRB
|
Nikola Milojević | 139 | 7 |
 BIH
|
Damir Džumhur | 140 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw using a protected ranking:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Nerman Fatić
Pavel Kotov
Fábián Marozsán
Luca PotenzaThe following player received entry as a lucky loser:
Holger Rune def. 
Cem İlkel 7–5, 7–6(8–6). Zdeněk Kolář / Jiří Lehečka def. Lloyd Glasspool / 
Harri Heliövaara 6–4, 6–4.
