The 2022 Epsom Derby was the 243rd annual running of the Derby horse race which took place at Epsom Downs Racecourse on 4 June 2022. The race was sponsored for the second time by the online car-dealer Cazoo.

Due to COVID-19 pandemic, the first entries were closed in February 2022.

The race was won by Desert Crown, owned by Suaeed Suhail, trained by Sir Michael Stoute and ridden by Richard Kingscote. It was Stoute's sixth win in the race and at 78 he became the oldest-known Derby-winning trainer. Kingscote was winning the Derby for the first time, in his second ride in the race.

Reference - Racing Post result

Winning time: 2 min 36.38 sec

* The distances between the horses are shown in lengths or shorter; shd = short head; hd = head; nk = neck.
† Trainers are based in Great Britain unless indicated.

Notable runs by the future Derby participants as two-year-olds in 2021

Early-season appearances in 2022 and trial races prior to running in the Derby: