The 2022 MotoE World Cup (known officially as the 2022 FIM Enel MotoE World Cup for sponsorship reasons) was the fourth season of the MotoE World Cup for electric motorcycle racing, and was a support series of the 74th Fédération Internationale de Motocyclisme (FIM) Road Racing World Championship season.

This was the last season of Energica being the sole supplier of the World Cup as they withdrew from the Cup after the season, with Ducati taking their place as the new sole manufacturer starting 2023.

Dominique Aegerter clinched the championship after a crash from Eric Granado during race 1 in Misano, his first MotoE crown.

All teams used the series-specified Energica Ego Corsa.

Starting this season, standard MotoE events featured two Free Practice sessions, a Qualifying on Friday, and two races: one on Saturday and the other on Sunday.

E-Pole was replaced by more traditional Qualifying sessions: Qualifying session format: Q1 (10 minutes) – 10 min break – Q2 (10 minutes).

The following Grands Prix took place in 2022:

Points were awarded to the top fifteen finishers. A rider had to finish the race to earn points.