The 2024 Missouri Senate election took place on Tuesday, November 5, 2024, with the primary election held on Tuesday, August 6, 2024. Missouri voters elected state senators in the 17 odd-numbered districts of the Senate to serve four-year terms. The last time that these seats were up for election was the 2020 Missouri Senate election, and the next time will be the 2028 Missouri State Senate election.

The election coincided with United States national elections and Missouri state elections, including U.S. President, U.S. Senate, U.S. House, Governor, and Missouri House.

Following the previous election in 2022, Republicans held a 24-to-10-seat supermajority over Democrats. Going into the 2024 elections, there are four vacancies after Senator Greg Razer (D) of District 7 resigned on April 25, 2024, Senators Karla Eslinger (R) of District 33 and John Rizzo (D) of District 11 resigned in June 2024, and Lauren Arthur (D) of District 17 resigned in July 2024. Therefore, there are 23 Republicans and seven Democrats at the time of the 2024 election (plus the three vacancies). Democrats would have to net 11 seats to flip control of the chamber.

These will be the first elections in the odd-numbered Missouri Senate districts following the 2020 United States redistricting cycle, which resulted in redrawn legislative district boundaries.

Districts where the margin of victory was under 10%:

Members of the Missouri General Assembly are prohibited from serving more than eight years in the state senate, due to statutory term limits.

Italics denote an open seat held by the incumbent party; bold text denotes a gain for a party.

Sources for election results: