Abd Allah ibn Ja'far ibn Abi Talib al-Hashimi (Arabic: عَبْدُ اللَّهِ ٱبْن جَعْفَر ٱبْن أَبِي طَالِب الْهَاشِمِي, romanized: ʿAbd Allāh ibn Jaʿfar ibn ʾAbī Ṭālib al-Hāshimī; c. 624 – 699 or 702/704) was a companion and relative of the Islamic prophet Muhammad, a nephew of Ali, a half-brother of Muhammad ibn Abi Bakr and grandfather of Abd Allah ibn Mu'awiya.

He was loyal to Ahl al-Bayt in spite of his absence at the Battle of Karbala. He is reported to have said: "Allah gave a chance to my two sons (Awn and Muhammad). I should have also been there. If I had been there I also would have sacrificed myself for Hussain Ibn e Ali." According to Richard Francis Burton he is widely recognized as the most sympathetic amongst Arabs. His grave is situated near Aqil ibn Abi Talib and Abu Sufyan ibn al-Harith (the grandson of Abd al-Muttalib) in al-Baqi Cemetery.

He was the son of Ja'far ibn Abi Talib and Asma bint Umays. They had emigrated to Abyssinia in 616, and Abd Allah and his two brothers were born there. Abd Allah was the first Muslim to be born in Abyssinia. After the birth of Abd Allah in Abyssinia (Habesha, now Ethiopia), the king of the Kingdom of Aksum (Najashi) also had a son. He immediately asked the parents of Abd Allah ibn Ja'far about the name of their child. Upon knowing the name, the king of Abyssinia also chose the name “Abd Allah” for his first son. It is also stated that Asma bint Umays was the nursing mother of the son of the Abyssinian King. The younger brother of Abd Allah appears to be the first child in Muslim history who was named Muhammad after the Islamic prophet. The family returned to Arabia in 628 and settled in Medina.

In addition to Ibn Hajar's reference, it is said that 3 days after Ja'far's death, Muhammad went to the house of Asma and called for the children of Ja'far. He then said about each of them: "As for Muhammad, he resembles our uncle Abi Talib. As for Abd Allah, he resembles me in terms of both my appearance and character." Afterward, Muhammad took the right hand of Abd Allah and said "O Allah, provide a successor for Ja'far in his family, and bless Abd Allah in his business, and repeated this appeal to the Almighty thrice. Muhammad instructed the sons of Abi Talib, namely Ja'far, Aqil and Ali that they should arrange marriages of their children with their cousins.

Ali had particularly wished that his daughters should marry Ja'far's sons. When Abd Allah asked for Zaynab's hand, Ali accepted it. Abd Allah and Zaynab had two children.

According to Shaykh Muhammad Abbas Qummi, Abd Allah had 20 sons from different wives, including five children from Zaynab bint Ali. The Daira-e-Maarif Islamia (Circle of Islamic Knowledge) of University of the Punjab (pages 568-70, Vol.X) describes Zaynabi as a progeny of Abd Allah’s son Ali through Zaynab bint Ali.

Abd Allah ibn Ja'far was one of the richest people in Medina and a philanthropist who was called as “Bahr al-Joud” which means an ocean of charity.

When Ali became the Caliph in 656 and moved from Medina to Kufa, Zaynab and Abd Allah joined him.