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Hub AI
Acrasin AI simulator
(@Acrasin_simulator)
Hub AI
Acrasin AI simulator
(@Acrasin_simulator)
Acrasin
An acrasin is a pheromone used by species of slime mold,[1] which signals to the many individual cells and triggers an aggregation response, such that they form a single large cell (a plasmodium). One of the earliest acrasins to be identified was cyclic AMP, found in the species Dictyostelium discoideum by Brian Shaffer,[2] which exhibits a complex swirling-pulsating spiral pattern when forming a pseudoplasmodium.[3]
The term "acrasin" is a reference to the character Acrasia in Edmund Spenser's Faerie Queene,[4] who seduced men against their will and then transformed them into beasts. Acrasia is itself a play on the Greek akrasia that describes loss of free will.
Brian Shaffer was the first to purify acrasin, now known to be cyclic AMP, in 1954, using methanol. Glorin, the acrasin of Polysphondylium violaceum, can be purified by inhibiting the acrasin-degrading enzyme acrasinase with alcohol, extracting with alcohol and separating with column chromatography.
Acrasin
An acrasin is a pheromone used by species of slime mold,[1] which signals to the many individual cells and triggers an aggregation response, such that they form a single large cell (a plasmodium). One of the earliest acrasins to be identified was cyclic AMP, found in the species Dictyostelium discoideum by Brian Shaffer,[2] which exhibits a complex swirling-pulsating spiral pattern when forming a pseudoplasmodium.[3]
The term "acrasin" is a reference to the character Acrasia in Edmund Spenser's Faerie Queene,[4] who seduced men against their will and then transformed them into beasts. Acrasia is itself a play on the Greek akrasia that describes loss of free will.
Brian Shaffer was the first to purify acrasin, now known to be cyclic AMP, in 1954, using methanol. Glorin, the acrasin of Polysphondylium violaceum, can be purified by inhibiting the acrasin-degrading enzyme acrasinase with alcohol, extracting with alcohol and separating with column chromatography.