Agnese Possamai (born 17 January 1953 in Lentiai) is a retired middle-distance runner from Italy. Her greatest achievements were the 1985 World Indoor silver medal as well as three European Indoor gold medals.

She won eleven medals at senior level (9 individual, 2 team) at the international athletics competitions. Her personal best times are 4:08.84 (1500 metres) and 8:37.96 (3000 metres). She has 60 caps in national team from 1977 to 1988.

Agnese Possamai has won 24 times the individual national championship.