Amanda Lepore is an American transgender model, singer, and performance artist. A former Club Kid, she has appeared in advertising for numerous companies. Lepore is noted as a regular subject in photographer David LaChapelle's work, serving as his muse, as well as many other photographers, such as Terry Richardson and Ruben van Schalm. She participated in LaChapelle's Artists and Prostitutes 1985–2005 exhibit in New York City, where she "lived" in a voyeuristic, life-sized set.

Lepore has released several singles, many written by and/or recorded with gay rapper and singer Cazwell. In 2011, she released her debut studio album, I...Amanda Lepore, on Peace Bisquit.

Amanda grew up in the Essex County community of Cedar Grove, New Jersey, with one sibling, an older brother. Her father was an Italian-American chemical engineer, and her mother was a German-American housewife. Her mother was diagnosed with schizophrenia, and spent considerable time in psychiatric hospitals. Lepore later wrote, "Ever since I can first remember, I knew I was a girl. I couldn't understand why my parents were dressing me up in boys' clothing. I thought they were insane."

When she was 15 years old, Lepore befriended a transgender dancer named Bambi. Realizing she was transgender from an early age, Lepore began sewing costumes for Bambi in exchange for female hormones. Having already grown isolated from her peers and schooling, Lepore's parents withdrew her from public school and hired a private tutor. They also took her to a psychologist, who successfully helped her obtain a prescription to begin hormone therapy.

At the age of 17, and through a legal loophole, Lepore married a male bookstore owner. She was granted permission for gender-affirming surgery, which she underwent at the age of 19, in Yonkers, New York.

In the early 1990s, Lepore intended to establish herself as an iconic nightlife figure (including becoming a key member of the Club Kids). She supported herself by working in a nail salon, as a part-time dominatrix, and later as a cosmetics salesgirl for Patricia Field. After meeting photographer David LaChapelle one evening, while hosting at Bowery Bar, she began collaborating with him and became a ‘muse’ of sorts for his work.

Lepore has had cameos in music videos for artists including Elton John, Thalía, the Dandy Warhols, Girl in a Coma, Grace Jones, Keanan Duffty, Sharon Needles, TIGA (for his cover of "Sunglasses at Night"), and the alt rock band the Drums (for "Days"). Lepore appears in many of Cazwell's music videos, including "Watch my Mouth" and "All Over Your Face".

She was Chief of Parade at the 2010 Sydney Gay and Lesbian Mardi Gras in Australia.