Prior to establishing D-Lab, Amy Smith likely engaged in various design and engineering projects that showcased her ingenuity and commitment to addressing real-world problems. Details of these earlier inventions and projects are scarce, but they likely contributed to her developing expertise and approach to invention.

Amy Smith and students at D-Lab developed various inventions and innovations including: " A portable, hand-powered grain grinder for use in rural communities. " A charcoal production system that reduces air pollution and improves fuel efficiency. " Simple and affordable water purification technologies to provide access to clean drinking water. These inventions are characterized by their low cost, simplicity, and suitability for local materials and conditions.

Amy Smith continues to lead the development of new appropriate technologies through D-Lab and other initiatives. Her work emphasizes user-centered design, collaboration with local communities, and a commitment to sustainability and social impact.