Community hub
Recent from talks
Contribute something to knowledge base
Content stats: 0 posts, 0 articles, 0 media, 0 notes
Members stats: 0 subscribers, 0 contributors, 0 moderators, 0 supporters
Subscribers
Supporters
Contributors
Moderators
Hub AI
Andrea Califano AI simulator
(@Andrea Califano_simulator)
Hub AI
Andrea Califano AI simulator
(@Andrea Califano_simulator)
Andrea Califano
Andrea Califano is a systems biologist. He is the Clyde and Helen Wu Professor of Chemical and Systems Biology at Columbia University Irving Medical Center, where he also holds appointments in the Departments of Biochemistry and Molecular Biophysics, Biomedical Informatics, and Medicine. Califano serves as the president of the Chan Zuckerberg Biohub New York.
Califano was born in Naples, Italy.[citation needed] He earned a Ph.D. in physics from the University of Florence in 1986 and completed postdoctoral training in optics at the Istituto Nazionale di Ottica in Florence, information mechanics at the Massachusetts Institute of Technology, and computational biology at the IBM T.J. Watson Research Center.
Califano began his career at IBM, where he established the company’s first Computational Biology group in 1990 and later became program director of the IBM Computational Biology Center in 1997. In 2000, he co-founded First Genetic Trust, a pharmacogenomics company focused on human polymorphisms and drug response.
He joined Columbia University in 2003 as Professor of Biomedical Informatics and was later named the Clyde and Helen Wu Professor of Chemical and Systems Biology. He founded the Department of Systems Biology in 2013, serving as its first chair until 2023. Califano also held leadership positions at the Herbert Irving Comprehensive Cancer Center, including Associate Director for Bioinformatics from 2007 to 2019 and Co-Leader of the Cancer Regulatory Network and Precision Oncology and Systems Biology Programs.
In 2010, Califano co-founded Therasis, a systems biology-based company focused on novel cancer treatments, and in 2015 co-founded DarwinHealth, a biotechnology company leveraging proprietary algorithms developed in his laboratory for precision oncology.
Califano is a contributor to website EXPeditions.
In 2023, he became President of the Chan Zuckerberg Biohub New York, an initiative dedicated to re-engineering the human immune system to detect and prevent cancer and neurodegenerative diseases.
Califano is known for pioneering the use of mammalian regulatory networks in modeling cancer-related phenotypes and identifying master regulator proteins that control cellular states. He introduced the OncoTecture hypothesis and formulated the Information Canalization Theory, which explains how conserved regulatory modules maintain homeostasis in both normal and diseased cells.
Andrea Califano
Andrea Califano is a systems biologist. He is the Clyde and Helen Wu Professor of Chemical and Systems Biology at Columbia University Irving Medical Center, where he also holds appointments in the Departments of Biochemistry and Molecular Biophysics, Biomedical Informatics, and Medicine. Califano serves as the president of the Chan Zuckerberg Biohub New York.
Califano was born in Naples, Italy.[citation needed] He earned a Ph.D. in physics from the University of Florence in 1986 and completed postdoctoral training in optics at the Istituto Nazionale di Ottica in Florence, information mechanics at the Massachusetts Institute of Technology, and computational biology at the IBM T.J. Watson Research Center.
Califano began his career at IBM, where he established the company’s first Computational Biology group in 1990 and later became program director of the IBM Computational Biology Center in 1997. In 2000, he co-founded First Genetic Trust, a pharmacogenomics company focused on human polymorphisms and drug response.
He joined Columbia University in 2003 as Professor of Biomedical Informatics and was later named the Clyde and Helen Wu Professor of Chemical and Systems Biology. He founded the Department of Systems Biology in 2013, serving as its first chair until 2023. Califano also held leadership positions at the Herbert Irving Comprehensive Cancer Center, including Associate Director for Bioinformatics from 2007 to 2019 and Co-Leader of the Cancer Regulatory Network and Precision Oncology and Systems Biology Programs.
In 2010, Califano co-founded Therasis, a systems biology-based company focused on novel cancer treatments, and in 2015 co-founded DarwinHealth, a biotechnology company leveraging proprietary algorithms developed in his laboratory for precision oncology.
Califano is a contributor to website EXPeditions.
In 2023, he became President of the Chan Zuckerberg Biohub New York, an initiative dedicated to re-engineering the human immune system to detect and prevent cancer and neurodegenerative diseases.
Califano is known for pioneering the use of mammalian regulatory networks in modeling cancer-related phenotypes and identifying master regulator proteins that control cellular states. He introduced the OncoTecture hypothesis and formulated the Information Canalization Theory, which explains how conserved regulatory modules maintain homeostasis in both normal and diseased cells.