Anna DiMera is a fictional character on the NBC daytime drama, Days of Our Lives. She was introduced as the estranged wife of Roman Brady and the biological mother of his daughter, Carrie Brady. Created by head writers, Margaret DePriest and Sheri Anderson, Anna is portrayed by Leann Hunley. Anna is known for being a member of the powerful, upper class DiMera family from her marriages to Tony DiMera.

Hunley initially portrayed Anna from 1982 to 1986. After a twenty-one year absence, Hunley reprised the role of Anna beginning on June 20, 2007, and remained on contract with the show until April 2, 2009. She then reprised the role again in early-December 2009 on a recurring basis, after taking a leave of absence from the show and ultimately leaving once more on June 15, 2010. In July 2016, it was reported that Hunley was to again reprise the role of Anna, with Anna returning from January 9 to February 16, 2017. In December 2017, it was announced that Hunley would return to the role, beginning January 5, 2018. She appeared until her departure again on February 14, 2018. In May 2019, it was announced that Hunley would reprise the role, beginning in July. On October 3, 2024, it was announced Hunley would reprise the role, when Anna returned on June 6, 2025.

For her portrayal of Anna, Hunley received a Daytime Emmy Award for Outstanding Supporting Actress in 1986.

Anna Fredericks first arrives in Salem in 1982, searching for Roman Brady, her husband and the father of her daughter, Carrie. For many years, Roman had been under the impression that Anna had been dead, when in reality she had been sold into slavery. Anna has several red marks on her back, which she claims are from being whipped but are in fact from multiple sclerosis.

Following her divorce from Roman, Anna takes a job as Tony DiMera's secretary, while working in secret for Stefano DiMera, who pays Anna $1,000,000 to have Roman fired from the ISA. To achieve this, Anna has Carrie hypnotized to place fake deposit slips in Roman's home. Although Roman is fired from the police force, the ISA are convinced that Roman had been framed.

In 1983, Anna drugs Tony and marries him in Las Vegas, which angers him. Shortly after the wedding, Tony discovers that one of the stipulations of Stefano's will require him to live with Renée DuMonde and David Banning for a year in order to gain his inheritance.

At one point in time, she discovers she is pregnant with Tony DiMera`s child, but suffers a miscarriage later on.

In 1986, Anna leaves Salem after learning Tony has divorced her. She moves to Europe, where she leads a successful career.