Anne Shakespeare (née Hathaway; 1556 – 6 August 1623), commonly known as Anne Hathaway, was the wife of William Shakespeare, an English poet, playwright and actor. They were married in 1582, when Hathaway was pregnant at 26 years old and Shakespeare was 18. Some writers, such as Schoenbaum, have assumed that she was rather old for an Elizabethan bride, but in fact it was normal for her contemporaries to marry in their 20s, although legally they could marry earlier. Shakespeare, on the other hand, was young for an Elizabethan bridegroom.

She outlived her husband by seven years. Very little is known about her life beyond a few references in documents. Her personality and relationship to Shakespeare have been the subject of much speculation by many historians and writers.

Anne Hathaway is believed to have grown up in Shottery, a village just to the west of Stratford-upon-Avon, Warwickshire, England. She is assumed to have grown up in the farmhouse that was the Hathaway family home, which is located at Shottery and is now a major tourist attraction for the village. Her father, Richard Hathaway, was a yeoman farmer. He died in September 1581 and left his daughter the sum of ten marks or £6 13s 4d (six pounds, thirteen shillings and fourpence) to be paid "at the day of her marriage".

In her father's will, her name is listed as "Agnes", leading to some scholars believing that she should be referred to as "Agnes Hathaway".

Hathaway married Shakespeare in November 1582, likely November 28, while already pregnant with the couple's first child, to whom she gave birth six months later. The age difference, added to Hathaway's antenuptial pregnancy, has been employed by some historians as evidence that it was a "shotgun wedding", forced on a somewhat reluctant Shakespeare by the Hathaway family. There is, however, no other evidence for this inference.

For a time it was believed that this view was supported by documents from the Episcopal Register at Worcester, which records in Latin the issuing of a wedding licence to "William Shakespeare" and one "Anne Whateley" of Temple Grafton. The following day, Fulk Sandells and John Richardson, friends of the Hathaway family from Stratford, signed a surety of £40 as a financial guarantee for the wedding of "William Shagspere and Anne Hathwey". Frank Harris, in The Man Shakespeare (1909), argued that these documents are evidence that Shakespeare was involved with two women. He had chosen to marry one, Anne Whateley, but when this became known he was immediately forced by Hathaway's family to marry their pregnant relative. Harris believed that "Shakespeare's loathing for his wife was measureless" on account of this forced marriage, and that this was the spur to his decision to leave Stratford and pursue a career in the theatre.

However, according to Stanley Wells, writing in the Oxford Companion to Shakespeare, most modern scholars take the view that the name Whateley was "almost certainly the result of clerical error".

Germaine Greer, in Shakespeare's Wife, argues that the age difference between Shakespeare and Hathaway is not evidence that he was forced to marry her, but that he was the one who pursued her. Women such as the orphaned Hathaway often stayed at home to care for younger siblings and married in their late twenties. As a husband Shakespeare offered few prospects; his family had fallen into financial ruin, while Hathaway, from a family in good standing both socially and financially, would have been considered a catch. Furthermore, a "handfast" and pregnancy were frequent precursors to legal marriage at the time. Examining the surviving records of Stratford-upon-Avon and nearby villages in the 1580s, Greer argues that two facts stand out quite prominently: first, that a large number of brides went to the altar already pregnant; and second, that autumn, not spring, was the most common time to get married. Shakespeare was bound to marry Hathaway, who had become pregnant by him, but there is no reason to assume that this had not always been his intention. It is nearly certain that the respective families of the bride and groom had known one another.