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Hub AI
Antimicrobial stewardship AI simulator
(@Antimicrobial stewardship_simulator)
Hub AI
Antimicrobial stewardship AI simulator
(@Antimicrobial stewardship_simulator)
Antimicrobial stewardship
Antimicrobial stewardship (AMS) refers to coordinated efforts to promote the optimal use of antimicrobial agents, including drug choice, dose, route of administration, and duration of therapy.
Every time an antimicrobial agent is used, whether or not that use is justified, it applies selective evolutionary pressure to microbial populations which can result in acquired antimicrobial resistance. Antimicrobial resistance genes can then spread to other microbes in the host or their environment, including those organisms that can live on your skin or in your body where they coexist with the host. Antimicrobial use can also cause additional unintended consequences, such as disruption to the normal microbiome (i.e., dysbiosis) as well as direct toxic effects on people and animals, including damage to kidneys, liver, teeth and bones. These unintended consequences are often referred to as “collateral damage”. Antimicrobial therapy is justified when the benefits outweigh these risks.
In 2007, the Society for Healthcare Epidemiology of America (SHEA) defined AMS as a "set of coordinated strategies to improve the use of antimicrobial medications with the following goals to:
Contrary to popular belief, AMS does not aim to reduce the overall volume or frequency of antimicrobial use, although that often happens to occur with successful AMS interventions. The aims of AMS are to:
Decreasing the overuse of antimicrobials is expected to serve the following goals:
Antimicrobial misuse was recognized as early as the 1940s, when Alexander Fleming remarked on penicillin's decreasing efficacy, because of its overuse. However, the first systematic assessment of antibiotic use wasn’t published until 1966 from a study that took place at Winnipeg General Hospital in Manitoba, Canada. Two years later, in 1968, others estimated that 50% of antimicrobial use was either unnecessary or inappropriate. In the 1970s, the first clinical pharmacy services were established in North American hospitals.
1980s
The first formal evaluation of antibiotic use in children was undertaken at The Children's Hospital of Winnipeg in 1980. Researchers observed errors in 30% of medical orders and 63% of surgical orders. The most frequent error was unnecessary treatment found in 13% of medical and 45% of surgical orders. The authors stated "Many find it difficult to accept that there are standards against which therapy may be judged."
Antimicrobial stewardship
Antimicrobial stewardship (AMS) refers to coordinated efforts to promote the optimal use of antimicrobial agents, including drug choice, dose, route of administration, and duration of therapy.
Every time an antimicrobial agent is used, whether or not that use is justified, it applies selective evolutionary pressure to microbial populations which can result in acquired antimicrobial resistance. Antimicrobial resistance genes can then spread to other microbes in the host or their environment, including those organisms that can live on your skin or in your body where they coexist with the host. Antimicrobial use can also cause additional unintended consequences, such as disruption to the normal microbiome (i.e., dysbiosis) as well as direct toxic effects on people and animals, including damage to kidneys, liver, teeth and bones. These unintended consequences are often referred to as “collateral damage”. Antimicrobial therapy is justified when the benefits outweigh these risks.
In 2007, the Society for Healthcare Epidemiology of America (SHEA) defined AMS as a "set of coordinated strategies to improve the use of antimicrobial medications with the following goals to:
Contrary to popular belief, AMS does not aim to reduce the overall volume or frequency of antimicrobial use, although that often happens to occur with successful AMS interventions. The aims of AMS are to:
Decreasing the overuse of antimicrobials is expected to serve the following goals:
Antimicrobial misuse was recognized as early as the 1940s, when Alexander Fleming remarked on penicillin's decreasing efficacy, because of its overuse. However, the first systematic assessment of antibiotic use wasn’t published until 1966 from a study that took place at Winnipeg General Hospital in Manitoba, Canada. Two years later, in 1968, others estimated that 50% of antimicrobial use was either unnecessary or inappropriate. In the 1970s, the first clinical pharmacy services were established in North American hospitals.
1980s
The first formal evaluation of antibiotic use in children was undertaken at The Children's Hospital of Winnipeg in 1980. Researchers observed errors in 30% of medical orders and 63% of surgical orders. The most frequent error was unnecessary treatment found in 13% of medical and 45% of surgical orders. The authors stated "Many find it difficult to accept that there are standards against which therapy may be judged."