Aparna Nancherla is an American stand-up comedian and actress. She has had recurring roles on television series including BoJack Horseman and Corporate and has written for Late Night with Seth Meyers and Totally Biased with W. Kamau Bell. Nancherla released her debut comedy album Just Putting It Out There through Tig Notaro's Bentzen Ball Records on July 8, 2016.

Aparna Nancherla was born in Washington, D.C., United States into an Indian Telugu Hindu family; her parents immigrated to the United States from Hyderabad, India in the 1970s. She has an older sibling, Bhavana.

She grew up outside Washington, attending Thomas Jefferson High School for Science and Technology in Fairfax County, Virginia. Nancherla attended Amherst College in Amherst, Massachusetts and studied psychology. She graduated in 2005.

After college she returned to Washington, D.C., where she began her standup career. Nancherla moved to Los Angeles, then to New York City to write for Totally Biased until the show's cancellation in 2013. Nancherla was subsequently a staff writer for Late Night with Seth Meyers in 2015.

Nancherla's credits also include several web series, including Your Main Thing with John Early, and co-created and starred in Womanhood, a satirical advice series with comedian Jo Firestone.

In 2019 she was featured in Laughing Matters, a 30-minute YouTube documentary created by SoulPancake in collaboration with Funny or Die wherein a variety of comedians discuss mental health.

Nancherla has appeared on Conan and Comedy Central's The Meltdown with Jonah and Kumail. Variety named her to its list of "Top 10 Comics to Watch for 2016" and The New York Times said that Nancherla "has become a comic in demand for her quirky, relatable and punchy humor." She is also the co-host of Blue Woman Group, which the Daily Beast calls "a hilarious podcast about depression."

In 2016, Comedy Central announced that Nancherla would record a half-hour special for the network.