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BGI Group

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BGI Group

BGI Group, formerly Beijing Genomics Institute, is a Chinese genomics company with headquarters in Yantian, Shenzhen. The company was originally formed in 1999 as a genetics research center to participate in the Human Genome Project. It also sequences the genomes of other animals, plants and microorganisms.

BGI has transformed from a small research institute, notable for decoding the DNA of pandas and rice plants, into a diversified company active in animal cloning, health testing, and contract research. BGI's earlier research was continued by the Beijing Institute of Genomics, Chinese Academy of Sciences. BGI Research, the group's nonprofit division, works with the Institute of Genomics and operates the China National GeneBank under a contract with the Chinese government. BGI Genomics, a subsidiary, was listed on the Shenzhen Stock Exchange in 2017. The company is supported by several China Government Guidance Funds and Chinese state-owned enterprises.

Starting in 2021, details came to light about multiple controversies involving the BGI Group. These controversies include alleged collaboration with the People's Liberation Army (PLA) and use of genetic data from prenatal tests. BGI denied that it shares prenatal genetics data with the PLA.

Wang Jian, Yu Jun, Yang Huanming and Liu Siqi created BGI, originally named Beijing Genomics Institute, in September 1999, in Beijing, China as a non-governmental independent research institute in order to participate in the Human Genome Project as China's representative. After the project was completed, funding dried up, after which BGI moved to Hangzhou in exchange for funding from the Hangzhou Municipal Government. In 2002, BGI sequenced the rice genome, which was a cover story in the journal Science. In 2003, BGI decoded the SARS virus genome and created a kit for detection of the virus. In 2003, the Chinese Academy of Sciences founded the Beijing Institute of Genomics in cooperation with BGI, with Yang Huanming as its first director. BGI Hangzhou and the Zhejiang University also founded a new research institute, the James D. Watson Institute of Genome Sciences, Zhejiang University.

In 2007, BGI broke away from the Chinese Academy of Sciences, became a private company, and relocated to Shenzhen. Yu Jun left BGI at this time purportedly selling his stake to the other 3 founders for a nominal sum. In 2008, BGI published the first human genome of an Asian individual.

In 2010, BGI bought 128 Illumina HiSeq 2000 gene-sequencing machines, which was backed by US$1.5 billion in "collaborative funds" over the next 10 years from the state lender China Development Bank. By the end of the year, they reportedly had a budget of $30 million. In 2010, BGI Americas was established with its main office in Cambridge, Massachusetts, US, and BGI Europe was established in Copenhagen, Denmark. By 2018, BGI opened offices and laboratories in Seattle and San Jose in US, and London in the UK, as well were founded BGI Asia Pacific with offices in Hong Kong, Kobe (Japan), Bangkok (Thailand), Laos, Singapore, Brisbane (Australia) and many others.[independent source needed]

In 2011, BGI reported it employed 4,000 scientists and technicians, and had a $192 million in revenue. BGI did the genome sequencing for the deadly 2011 Germany E. coli O104:H4 outbreak in three days and released it under an open license. Since 2012, it has started to commercialize its services, having investments from China Life Insurance Company, CITIC Group's Goldstone Investment, Jack Ma's Yunfeng Capital, and SoftBank China Capital. That year they also launched their own scientific journal, GigaScience, partnering with BioMed Central to publish data-heavy life science papers. A new partnership was subsequently formed between the GigaScience Press department of BGI and Oxford University Press and since 2017 GigaScience has been co-published with the Oxford University Press.

In 2013, BGI bought Complete Genomics of Mountain View, California, a major supplier of DNA sequencing technology, for US$118 million, after gaining approval from the Committee on Foreign Investment in the United States. Complete Genomics is a US-based subsidiary of MGI, MGI was a subsidiary of BGI before it was spun out and listed on the Shanghai Stock Exchange in 2022.

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