Boss Ko (14 October 1974 – 24 December 2021) was a Burmese politician who served as acting Chief Minister of Kayah State, Minister of Agriculture, Livestock and Irrigation for Kayah State and Kayah State Parliament MP for Demoso Township Constituency No. 2.

Boss Ko was born on 14 October 1974 in Puphar village, Demoso, Kayah State, Myanm to parents U Thung and Mushi. He finished high school in Loikaw.

He was a member of the National League for Democracy Party. In the 2015 Myanmar general election, he contested the Demoso Township constituency No. 2 for Kayah State Parliament and won a seat. He was appointed Minister of Agriculture, Livestock and Irrigation for Kayah State on 7 April 2016, and acting Chief Minister on 3 September 2020 by President Win Myint, after chief minister L Phaung Sho was relieved from post. He served until the 1 February 2021 military coup d'état in Myanmar. He was detained by the military council after the coup.

Ko died on 24 December 2021, at the age of 47 after he escaped from prison.