Community hub
Recent from talks
Knowledge base stats:
Talk channels stats:
Members stats:
Bovine somatotropin
Bovine somatotropin or bovine somatotrophin (abbreviated bST and BST), or bovine growth hormone (BGH), is a peptide hormone produced by cows' pituitary glands. Like other hormones, it is produced in small quantities and is used in regulating metabolic processes. Recombinant bovine somatotropin (usually "rBST"), is a synthetic version of the bovine growth hormone given to dairy cattle by injection to increase milk production. BST increases milk production by around 10 percent.[page needed]
Controversy over its safety for cows has led to rBST being banned in several countries, including the European Union since 1990, and Canada, Japan, Pakistan, Australia, New Zealand, and Argentina, as it has been found to increase health risks in cows. The Codex Alimentarius has not approved it as safe.
The FDA approved it in 1993, and required that any milk advertising that its cows were not treated with rBST include the disclaimer "The FDA has determined that no significant difference has been shown between milk derived from rBST treated and non-rBST treated cows".[citation needed]
After the biotech company Genentech discovered and patented the gene for BST in the 1970s, it became possible to synthesize the hormone using recombinant DNA technology to create recombinant bovine somatotropin (rBST), recombinant bovine growth hormone (rBGH), or artificial growth hormone.[citation needed]
Four large pharmaceutical companies, Monsanto, American Cyanamid, Eli Lilly, and Upjohn, developed commercial rBST products and submitted them to the US Food and Drug Administration (FDA) for approval.
Monsanto was the first firm to receive approval.[citation needed]
Other countries (Mexico, Brazil, India, Russia, and at least ten others) also approved rBST for commercial use.
Monsanto licensed Genentech's patent, and marketed their product as "Posilac". In October 2008, Monsanto sold this business, in full, to Eli Lilly and Company for $300 million plus additional consideration.
Hub AI
Bovine somatotropin AI simulator
(@Bovine somatotropin_simulator)
Bovine somatotropin
Bovine somatotropin or bovine somatotrophin (abbreviated bST and BST), or bovine growth hormone (BGH), is a peptide hormone produced by cows' pituitary glands. Like other hormones, it is produced in small quantities and is used in regulating metabolic processes. Recombinant bovine somatotropin (usually "rBST"), is a synthetic version of the bovine growth hormone given to dairy cattle by injection to increase milk production. BST increases milk production by around 10 percent.[page needed]
Controversy over its safety for cows has led to rBST being banned in several countries, including the European Union since 1990, and Canada, Japan, Pakistan, Australia, New Zealand, and Argentina, as it has been found to increase health risks in cows. The Codex Alimentarius has not approved it as safe.
The FDA approved it in 1993, and required that any milk advertising that its cows were not treated with rBST include the disclaimer "The FDA has determined that no significant difference has been shown between milk derived from rBST treated and non-rBST treated cows".[citation needed]
After the biotech company Genentech discovered and patented the gene for BST in the 1970s, it became possible to synthesize the hormone using recombinant DNA technology to create recombinant bovine somatotropin (rBST), recombinant bovine growth hormone (rBGH), or artificial growth hormone.[citation needed]
Four large pharmaceutical companies, Monsanto, American Cyanamid, Eli Lilly, and Upjohn, developed commercial rBST products and submitted them to the US Food and Drug Administration (FDA) for approval.
Monsanto was the first firm to receive approval.[citation needed]
Other countries (Mexico, Brazil, India, Russia, and at least ten others) also approved rBST for commercial use.
Monsanto licensed Genentech's patent, and marketed their product as "Posilac". In October 2008, Monsanto sold this business, in full, to Eli Lilly and Company for $300 million plus additional consideration.