Breadsall Priory is a former Augustinian priory in Derbyshire, situated around two kilometres north of Breadsall, and two kilometres east of Little Eaton. The priory was established before 1266 by a member of the Curzon family. Only a small priory, Breadsall was dissolved in 1536.

Following dissolution the priory was demolished and a private home, also known as Breadsall Priory, built on the site; the house was altered and extended in both the 19th and 20th centuries, and only a single arch remains of the monastic buildings. The house and its stables are both Grade II Listed. The house is currently used as a hotel, while its stables are in residential use.

Breadsall Priory was established before the middle of the 13th century by one of three generations of the Curzon family: Richard, Henry or Sir Robert Curzon (grandfather, son and grandson).

Many sources often mistakenly refer to Breadsall as being a house of Augustinian Friars (also known as Friars Eremites), due to a mistake made on a Patent Roll in 1266. Breadsall was in fact home to Augustinian Canons; a fact confirmed by King Henry III's grant of 20 acres of land in Horsley and Horston: Augustinian Friars could not own any land other than what their priory sat upon; Augustinian Canons, however, could freely own land.

Breadsall Priory was very small. Breadsall was usually home to only the prior and two canons, and the taxation roll of 1291 reveals that the priory had an annual income of only £5 19s. However, Breadsall was frequently home to just the prior and one canon, or just the prior alone. The small number of canons made it impossible to elect a prior, meaning one was often chosen by a member of the Curzon family, who served as "hereditary patrons". The Curzon family were Lords of the Manor of Breadsall Overhall for eight generations.

During the reign of King Richard II (1377–1399), the manor passed to the Dethick family, through the marriage of Cecilia Curzon to William Dethick. However, the Dethick family's relationship to the priory was, for a period, unclear. In 1384, the appointment of the prior was made by Sir Thomas Wendesley, who was referred to as Patron pro hac vice. Several other priors were also appointed by the Bishop of Lichfield, rather than the Dethick family. However, in 1456 the bishop confirmed Sir William Dethick's right to "the first licence to elect or provide a superior when the priory was vacant".

In 1402 William Dethick, son of Cecilia Curzon, donated a moiety of the rectory of Mugginton to Breadsall. Dethick had, however, failed to follow proper procedure to alienate the lands; thus, upon his death, his "executors and trustees" were "heavily fined" by the crown.

In 1444, Breadsall Priory was sued by the Collegiate Church of St Mary in Leicester, over the tithes of a field called "Hethfield", near Mugginton. St Mary's argued that the field belonged to the Parish of Duffield (which was in their control), and not that of Mugginton (controlled by the priory). The court found in favour of St Mary's and control of the field passed to the collegiate church. The rector of Mugginton was "condemned for contempt of Court of Arches" and ordered to pay the 40s. to St Mary's.